Popular Searches

News and Activities


News and Activities

  • Congratulations to Revan and Yang on their contributions to the collaborative study with NIH/NIAID and Columbia University, "HIV-1 Envelope Trimer Transitions from Prefusion-Closed to CD4-Bound Open Conformations Through an Occluded Intermediate State," published in the Computational and Structural Biotechnology Journal! Read the full article here: Link to the article. 

  • Congratulations to Wang and Yang on their publication, "Multi-step Shapeshifting of SARS-CoV-2 Omicron Spikes During Fusion," in Structure!  

  • Check out the special research collection entitled "Viral Surface Spikes: Host Cell Entry, Immune Responses and Evasion, and Implications for Viral Infection, Inhibition and Rebound."Now, it is open for submission.

    This research topic, developed in alignment with the objectives of the Duke Center for HIV Structural Biology (DCHSB), has been expanded to include a diverse range of viral pathogens and host systems. We invite submissions of Original Research, Reviews, and Mini-Reviews on the following topics:

    i) Molecular mechanism of viral spike-mediated host cell entry and immune evasion, ii) Innate and adaptive immune responses to viral surface spike glycoproteins, iii) Structure-based vaccine design and antibody therapies targeting viral spike proteins, iv) Antigenic profiling of spike proteins and strategies to block viral infection and rebound, v)Mechanisms of action for anti-spike antibodies, peptide inhibitors, and small molecules, and vi) Spike protein-mediated virus-to-cell fusion and cell-to-cell transmission.