Professor, Biochemistry
Phone: 903.877.7938
Email: hua.tang@uttyler.edu
Department: Cellular and Molecular Biology
Hua Tang
Dr. Tang is currently a Professor of Biochemistry. Dr. Tang has a broad background in Biochemistry, Cell Biology and Medicine, with specific training and expertise in protein kinases, phosphatases, and signal transduction. His research focuses on defining the molecular mechanisms that underlie the development of acute lung diseases. His group has extensively worked on the regulation of lung epithelial barrier function and permeability, lung epithelial cell signaling and cell death such as apoptosis and necroptosis under normal and inflammatory conditions in vitro and in vivo. He is particularly interested in understanding the role of necroptosis of pulmonary epithelial cells and macrophages in acute lung injuries resulting from infections to sterile inflammation. A major goal is to develop cell type-specific necroptosis inhibitors to treat various forms of acute lung injuries. Dr. Tang also investigates the role of transcription factor Runx3 in host immune response to lung infection and injury. His group has recently developed inducible general and conditional Runx3 knockout mouse models for the study of influenza infection.
Education & Training
Vanderbilt University - Nashville, TN
Post Doc, Biochemistry, 1994-1998
Shanghai Medical University - Shanghai, China
PhD, Biochemistry, 1988-1993
Courses Taught
BIOT 5222/5222L: Advanced Metabolism: Sugars and Polysaccharides
BIOT 6311: Advanced Techniques in Molecular Biology
BIOT 5211/5211L: Advanced Biotechniques
BIOT 5132: Critical Reading II Class
Research Interest
- To identify the mediators that regulate necroptosis of lung tissue cells during acute
lung injury
• To develop cell type specific necroptosis inhibitors for the treatment of acute lung injury and inflammation
• To define the role of Runx3 in host innate and adaptive immune responses to respiratory virus infection
Publication Highlights