Assistant Professor, Research
Phone: 903.877.7224
Email: tsuyoshi.sakai@uttyler.edu
Department: Cellular and Molecular Biology
Tsuyoshi Sakai
Dr. Sakai has published peer reviewed publications twenty times starting in 1996, including publications in Nature Structural and Molecular Biology, PNAS, JCB and JBC. He has given twenty-two presentations in four different countries (USA, Japan, China, and Austria) to scientific organizations since 1995. He has been working as an assistant professor for research in Tyler since 2019.
Education and Training
- BA, Bioengineering
Japan, Soka University 1994 - MD, Bioengineering
Japan, Soka University 1996 - PhD, Physiology
Japan, Soka University: Function of transcription factor. 2003
Courses Taught
Mutagenesis, Gene editing, Protein chemistry, Protein-protein interactions, FRAP assay
and Cell migration assay in Biotechnology Master’s program.
Research Interests
For Dr. Sakai research has been focused on biochemical and molecular characterization of diseases-linked motor proteins. Motor proteins represent the fundamental source of motive force in living systems such as muscle contraction, cell division, intracellular trafficking, cell locomotion, endocytosis, phagocytosis, epithelial sheet closure in development, wound healing, neuronal path finding, immune cell function, cell invasion, metastasis of cancer cells and vesicle transport. Recent progress of the research has raised a hypothesis that each motor protein has unique motor characteristics, specific docking partners and has a specific cellular function. Yet the physiological function and regulation of motor proteins are far from understood. He has recently been collaborating in CMBR to study the role of motor protein and transcription factor-related regulation mechanism that is associated with progress of lung fibrosis.
Publication Highlights