Publications

Recent Peer Reviewed Publications
Updated Publication List

Signaling Crosstalk in Staphylococcus aureus Two-component Systems Network. L Ali and MH Abdel Aziz#. (2024) J. Bacteriol. 206(4):e0041823
 
Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human Topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma. AI Khodair, SM El-Hallouty, B Cagle-White, MH Abdel Aziz, MK Hanafy, S Mowafy, NM Hamdy, SE Kassab. (2024) Eur. J. Med. Chem. 265: 116049.
 
A Scoping Review of Artificial Intelligence within Pharmacy Education. MH Abdel Aziz#, C Rowe, R Southwood, A Nogid, S Berman, K Gustafson. (2024) Am. J. Pharm. Educ. 88: 100615.
 
NH125 Sensitizes Staphylococcus aureus to Cell Wall Targeting Antibiotics through the Inhibition of VraS Sensor Histidine Kinase. S Bhattarai. L Marsh, K Knight, L Ali, A Gomez, A Sunderhaus, MH Abdel Aziz#. (2023) Microbiol. Spectr. 11(3):e0486122.
 
Pharmacy students’ perceptions and attitudes toward face-to-face vs. virtual team-based learning (TBL) in the didactic curriculum: A mixed-methods study. O Shoair, WJ Smith, MH Abdelaziz, M Veronin, J Glavy, S Pirtle. (2023) Med Educ Online 28(1):2226851.
 
A FOXC2 inhibitor, MC-1-F2, as a therapeutic candidate for targeting EMT in castration-resistant prostate cancer. M Castaneda, L Rodriguez; J Oh; B Cagle-White; H Suh; MH Abdel Aziz, J Lee. Bioorg. Med. Chem. Lett. 91 (2023) 129369.

Recent Invited Presentations

Medicinal Chemistry: Healing by Design. MH Abdelaziz. Presented at ACS National Chemistry Week. UT Tyler, October 16, 2023.
 
The Effect of the Staphylococcus aureus Histidine Kinase VraS Mutations on Catalysis, Substrate Affinity, and Antibiotic Resistance. MH Abdelaziz. Presented at UT Health Science Center at Tyler. May 30, 2023.
 
Kinases: At the Crossroads of Human and Bacterial Cell Signaling. MH Abdelaziz. Presented at the FCOP Research Seminar Series. May 9, 2023.
 
Biomedical Research APPEs: Opportunities and Challenges. MH Abdelaziz. Presented at the FCOP Preceptor Conference. December 10, 2022.
 
Engineered tyrosine kinase receptor dimers as a drug discovery tool. MH Abdelaziz. Podium Presentation at the Southern Biomedical Engineering Conference. August 27, 2022.

Recent Posters/Presentations

 The Effect of VraS Single Point Mutation on Staphylococcus aureus Gene Expression during Vancomycin Shock: A Bioinformatic Analysis. S Karki, L Ali, S Srivastava, MH Abdelaziz. Presented at the UT Tyler Lyceum, Tyler, TX. April 26, 2024. 
 
Exploring Crosstalk Interactions in the Two-Component System Signaling Network of Staphylococcus aureus.  D Al-manaseer, A Mattern, L Ali, S Karki, and MH Abdelaziz. Presented at the UT Tyler Lyceum, Tyler, TX. April 26, 2024. 
 
Molecular Mechanism of Pseudomonas-induced Activation of Epidermal Growth Factor Receptor. E Nwachukwu, S Fancher, B Cagle-White, MH Abdel Aziz, D Patterson, A Azghani. Presented at the East Texas Research Conference. Tyler, TX. April 12, 2024.
 
The effect of Staphylococcus aureus’ VraS kinase domain mutations on VraR interaction affinity and activation. A Solis, B Cagle-White, L Marsh, S Bhattarai, MH Abdel Aziz. Presented at the National American Society of Microbiology Conference, Houston, TX. June 16, 2023. 
 
The impact of Staphylococcus aureus VraS histidine kinase mutation on antibiotic resistance. L Ali, B Cagle-White, K Knight, MH Abdel Aziz. Presented at the National American Society of Microbiology Conference, Houston, TX. June 18, 2023. 
 
Engineering polycaprolactone composite nanofiber as antibacterial wound healing scaffolds. I Montoya, S Karki, S Sulthana, S Aryal, O Alsmairat, MH Abdel Aziz. Presented at the UT Tyler Lyceum, Tyler, TX. April 14, 2023. 
 
Investigating the Mechanism of Pseudomonas-induced Activation of Epidermal Growth Factor Receptor in vitro. E Nwachukwu, B Cagle-White, MH Abdel Aziz, A Azghani. Presented at the Texas Branch–American Society for Microbiology. March 25, 2023.
 
Design and characterization of electrospun nanofiber membrane for antibacterial drug delivery.
S Karki, A Neelam, B Cagle-White, A Solis, L Ali, O Alsmairat, S Aryal, MH Abdel Aziz. Presented at the Southern Biomedical Engineering Conference. August 26, 2022. (Third place, Undergraduate Student Poster Award).
 
Exploring the effect of mutations on the activity and stability of the bacterial histidine kinase VraS. E Scott, A Sunderhaus, S Bhattarai, K Catague, B Cagle-White, MH Abdel Aziz. Presented at the ACS National Meeting. March 21, 2022.
 
Activation of VraS histidine kinase by T331I mutation linked to antibiotic resistance. S Bhattarai, A Sunderhaus, L Marsh, and MH Abdel Aziz. Selected for the “Live Poster” session at the ACS National Meeting. April 10, 2021.
 
Modulation of VraS Sensor Histidine Kinase Activity and Inhibition in Presence of its Response Regulator VraR. L Marsh, S Bhattarai, A Sunderhaus, P Epie, and MH Abdel Aziz. Presented at the Texas Academy of Science. February 27, 2021.